Cross-Sphere

Finding The Author: A group of hunters known as The Children of Athanasius have identified a powerful relic in an attempt to gain the upper hand in destroying the non-supernatural.

Vampire-Centric

The Children Of Athanasius: Prince Winder has launched an investigation into a group of chillingly-informed vampire hunters announced themselves to the Bay area with an execution film in the guise of a supernatural thriller movie. Meanwhile, a group of vampire hunters have reportedly kidnapped the Sabbat pack, The Iron Shields, and each Sect wants to track them down, whether to recover their brethren or leverage the missing vampires as a lead to exterminate the hunters.

Sutro Baths: The Technocratic Union has taken over a node previously occupied by a mysterious, violent monster.

Drug Syndicates: San Francisco's opiate crisis has been worsened not only with fentanyl, but the introduction of untraceable ghost guns.
SF Open Heart: A homeless advocacy group is trying to make a dent in the drug crisis.